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The current DEN immunization strategy favors the use of live-attenuated vaccines which offer the advantage of a single dose, delivering a complete set of protective antigens and achieving a long-lasting immunity [4].
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The targeted intraoperative radiotherapy technique consists of a single dose delivered concurrently with lumpectomy.
1.6 2 Gy were considered normofractionated (nFSRT), 2.8 5 Gy were considered hypofractionated (hFSRT), and high single doses delivered in less than 5 sessions were considered stereotactic radiosurgery (SRS).
Therefore, sequential doses of ABT-737 12 16 h apart may be more effective than a single-dose delivered at the same time as immunotherapy.
Potency was high: a single NP dose delivering picomolar quantities of LIF is sufficient to increase remyelination.
A major challenge for poultry vaccination is the design of vaccines that protect against multiple pathogens via a single protective dose delivered through mass vaccination methods.
The present study was designed to evaluate the time course and manner of Purkinje cell death following a single ethanol dose delivered intragastrically on postnatal day (PN) 4 to rat pups.
A possible reason is that a single high dose delivered in short time might induce reactive edema and inflammation of tumor cells, which would lead to a slight increase of tumor volume.
A single dose was delivered by intrathecal injection to medically stable SMA patients 2-14 years of age.
Innovative vaccine platforms composed of adaptable adjuvants able to appropriately modulate immune responses, induce long-lived immunity in a single dose, and deliver immunogens in a safe and stable manner via multiple routes of administration are needed.
To examine the efficacy and feasibility of the IMDDS, we investigated the pharmacokinetic behavior of dexamethasone in plasma after a single dose was delivered via the modified implant placed in the rabbit tibia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com