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It is worth note that about the two thirds of differentially expressed genes in each lineage choice are specific of a single differentiation program (e.g. 273 out of 403 genes differentially expressed in CD34+ cells versus monoblasts are specifically differentially expressed only in this comparison).
Treatment of differentiating cultures with 4-OHT allowed for controlled deletion of Brg1 at specific stages of differentiation and allowed for the comparison of control and treatment groups within a single differentiation, which limited confounding effects from differentiation variability.
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But to the court, this single technological differentiation isn't enough to call Aereo's service private performance instead of public.
But to the court, this single technological differentiation isn't enough to call Aereo's service private performance instead of public.
Thus, the concept of a single encoded differentiation pathway within the system was rejected.
Thus cotton fiber is a model system to study single cell differentiation, development, and maturation of other plants cells.
detected at only a single site, differentiation amongst populations could not be assessed on Anjouan.
The protein extracts were derived from one well of a six well plate of a single neuronal differentiation.
It is also not clear if the ability of the progenitor/stem cells to react with a diversity of markers is a reflection of different transient stages within a single cell differentiation pathway or is an indication of different subpopulations.
At the protein level, the neuronal cells which we derived from sporadic AD-iPSCs in a single neuronal differentiation experiment expressed p-tau and GSK3B, both valid as neuropathological proteins.
We considered that there might be two possible explanations for this discrepancy with our model: (i) Gata1 regulates a protein not present in our network, and this can generate this second 'push' or (ii) there is a missing link in our wiring diagram, which when introduced would increase the 'power' of Gata1 so that its ectopic expression would become a single push differentiation trigger.
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