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Further studies on additional low and high passage strains should reveal whether the loss of the vls cassette is the major or even single causative event which leads to loss of infectivity.
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This complex situation indicates that multiple subcellular failure in selected cell populations is difficult to reconcile with a reductionistic scenario of a single causative cascade of events leading to non-motor symptoms in PD.
Therefore the effect size of a single causative variant should be modest [ 22].
Constitutive activation of β-catenin-dependent gene expression is almost certainly a key causative event in the genesis of colon and some other cancers.
Polymerization of the soluble β-amyloid peptide into highly ordered fibrils is hypothesized to be a causative event in the development of Alzheimer's disease.
It is concluded that the causative event must have been a tsunami that was most likely generated within the Makran Subduction Zone.
Activation of the RET gene by chromosomal rearrangements generating RET/PTC oncogenes is a frequent, early, and causative event in papillary thyroid carcinoma (PTC).
Despite this, a single causative gene is yet to be identified, largely due to substantial genetic heterogeneity.
Often there is no one causative event for FM.
I think a natural disaster, a natural property disaster, could be a causative event that could turn the market".
There is no single causative agent of bacterial vaginosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com