Sentence examples for single and in combination with from inspiring English sources

Literature reports many analytical methods for the determination of CEF in single and in combination with other drug, using UV spectroscopy [10, 11] spectrofluorometry [12] HPLC [13 20] and HPTLC [21].

Poly (ADP-ribose) polymerase (PARP) inhibitors represent an exciting class of drugs that have demonstrated promise in clinical BRCA1/2-related cancers as single agents [ 37, 38] and in preclinical studies as single agents and in combination with certain classes of DNA-damaging agents [ 39, 40].

Leverson, J.D. et al. Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).

HCC cell lines and xenograft models were used to determine the antitumor activity of SGI-110 as a single agent and in combination with oxaliplatin.

Preclinical and clinical evaluations of a variety of Hsp90 inhibitors have shown anti-tumor effect as a single agent and in combination with chemotherapy.

This review summarizes several landmark trials utilizing rituximab as a single agent and in combination with chemotherapy for treatment of NHL.

Inhibition of the prosurvival Bcl-2 family proteins has become a strategy for cancer therapy and inhibitors are currently being evaluated in the clinic both as single agents and in combination with established drugs.

As a result, small molecules designed to specifically target Akt and other components of the pathway are now being developed for clinical use as single agents and in combination with chemotherapy to overcome therapeutic resistance.

We evaluated the effectiveness of PBO long-lasting insecticidal nets versus standard long-lasting insecticidal nets as single interventions and in combination with the indoor residual spraying of pirimiphos-methyl.

Leow CC, Chesebrough J, Coffman KT, Fazenbaker CA, Gooya J, Weng D, et al. Antitumor efficacy of IPI-504, a selective heat shock protein 90 inhibitor against human epidermal growth factor receptor 2-positive human xenograft models as a single agent and in combination with trastuzumab or lapatinib.

In this report, we evaluated the effects of TRC105 on primary human umbilical vascular endothelial cells (HUVEC) as a single agent and in combination with bevacizumab.