Exact(1)
It remains unclear whether this CCL2-mediated pathway after AR blockade contributes to the development of CRPC, since this progression represents the major failure of ADT and shortens the survival of PCa patients (Garcia & Rini, 2012).
Similar(59)
This is important since the progression from latent infection to active disease is increased in contacts of index cases infected with M. tuberculosis compared to M. africanum indicating a potential role for the bacteria in determining the outcome of the host immune response [29], [30].
Since the progression of sarcopenia induces significant physical depression [ 20– 22], this condition increases the risk of fractures due to fall and the possibility of becoming bedridden in elderly people.
To this end, oncogenic KRAS-driven lung tumour models will be useful since the progression of early precursor lesions into malignant adenocarcinoma can be tracked in these models (Jackson et al, 2001; Mainardi et al, 2014).
This is of particular interest in the context of biomedical diagnosis, since the progression from normal to pathological tissue is often characterized by changes in the relative abundance of tissue fluorophores.
Since the progression of tumours requires the development of capillaries (a process known as angiogenesis) that supply tumour cells with oxygen and nutrients, interfering with this essential step is a promising therapeutic approach.
Since the progression of renal damage is slow, if discontinuing lithium is deemed necessary, the second mood stabilizer should be added, titrated to full dose and only then should the lithium be tapered and discontinued gradually over 4 8 weeks.
Since the progression of Abeta pathology in our colony is slower than that in the original colony [37], we started the treatment of mice at the age of 13 months (13.2±0.6).
These actin structures are essential for the completion of epiboly, since the progression of epiboly can be interfered by disrupting actin rings using cytochalasin B. The actin condensation at the front margin of deep cells we observed in this study is more like the so-called "mesh-like network" of cortical microfilaments described in Cheng's study.
Since the progression of the glioma tumours largely depends on the angiogenesis and the microvascular proliferation, the key idea is to study the BVs of these tumours by vibrational spectroscopy to see if this can help to identify different issues.
Since the progression of age-related cataract in humans is slow, the anti-cataract drug must be applied for a longer duration, as we used KCD eye drops during this study.
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