Exact(2)
Animal models are therefore necessary to study the physiopathology of preeclampsia, however, since this pathology is specifically human, there are no spontaneous models.
However, since this pathology is often accompanied with depression and neurodegenerative disorders, we had an important number of subjects with NP that were excluded of the study.
Similar(58)
On the other hand, the uterus or fetus is probably not necessary for the development of this pathology, since there have been reports of preeclampsia with abdominal pregnancies [ 102] or hydatidiform moles [ 103].
Moreover, the description of extra-cerebral disease is probably not the best suited variable for this pathology, since the prognosis of women with bone metastases or locoregional recurrences differs from that of patients with liver or lung metastases.
The presence of glutathione peroxidase 3 in equalized plasma of Rheumatic Mitral Stenosis raises the possibility of a protective role in this pathology, since it modulates oxidative stress by increasing resistance of cells to such kind of vascular injury.
Moreover the median age was slightly higher than had been previously reported which could be related to the introduction of several novelties in the treatment of severely ill patients since the identification of this pathology.
This is important since the pathology of frontotemporal lobar degeneration is as likely as Alzheimer's disease with onset below age 65 (Ratnavalli et al., 2002), whereas Alzheimer's disease pathology is much more commonly associated with degenerative syndromes above age 65.
Furthermore, since the pathology of these disorders is often only discernable in aged populations, testing the therapeutic value of small molecules in vertebrate disease models requires time consuming and costly experimental designs.
Since the pathology, diagnosis, and treatment vary between the two forms of disease, a potential merger of the two disease belts would cause major public health crises [ 2].
In patients with chronic pulmonary disease it is the pathological destruction of the lung parenchyma that disrupts V ˙ / Q ˙ and since the pathology is often unevenly distributed throughout the lungs, the V ˙ / Q ˙ mismatch is said to be heterogeneous.
This is particularly useful since the pathologies underlying behavioural variant FTD are notoriously heterogeneous and difficult to predict based on clinical features alone (Josephs et al., 2011).
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