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Since this assay is carried out in homogeneous solution phase under isothermal condition and sophisticated probe immobilization processes are avoided, it is very simple and easy to implement.
This is close to the cut-off of 30% that was applied in assay 463, which is not surprising since this assay contributed ~17 times as many measurements as assay 364.
Since this assay pertains only to the coagulation pathway, the three platelet-related polymorphisms were not considered for this analysis.
Since this assay had never been performed in nuclear lysates, we optimized a nuclear isolation protocol with emphasis on speed and purity of the isolated fractions (see Methods).
Since this assay only reports the point of phagosomal acidification, we had no way of determining the exact point of bead internalization.
To examine cause-effect relationship between extracellular fibrils formation and hypervirulence by a complementary approach, we utilized in vitro fungus PMN assay since this assay is rapid and results correlate well with virulence properties seen in animal model [31], [63].
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The significance of the bacterial reverse mutation test has been clearly confirmed as a suitable primary test for the detection of potential mutagens and carcinogens, and since midseventies this assay has been routinely used as a screening assay to predict carcinogens [ 32].
Apart from applying in PMI estimation and time since deposition estimation, this assay can also be used for environmental degradation assessment of biological sample & its repair (Lehmann 2003; Hall et al. 2004; Hall et al. 2014; Nelson et al. 2009).
Since performance of this assay does not appear to be influenced by differences in HIV-1 subtypes A, C and D, it has the potential for use in the detection of HIV-1 DNA in samples from geographic areas where these subtypes are prevalent.
This assay has since been modified to include a monoclonal capture antibody; however, no commercial assays for measuring antibodies in oral fluid are available.
It should be noted that it is difficult to monitor progression beyond one cell cycle in this assay since the iC2C12-FRG1 myoblasts rapidly lose synchronicity.
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