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Since long term rodent carcinogenicity studies are used to test a very large number of potential tumor endpoints, finding a balance between the control of Type 1 and Type 2 error is challenging.
And, since long term planning and investing for the future are not new concepts, it seems to be a new way of saying old things.
"In presenting the package," he writes, "you can bill it as the largest hedge fund blow up since Long Term Capital Management's in...1998".
However, significant challenges remains for hESC culture, since long term culture and passages of hESCs lead to significant changes of copy number variations (CNVs) and gene expressions [51].
Since long term changes in the expression of multiple proteins, such as seen in this study, are often related to epigenetic modification of the promoter region of genes, we have initiated epigenetic studies to identify these changes.
Since long term use through the third trimester appears to impart greater risk of neonatal abstinence syndrome, minimizing the use of prescription opioids towards the end of pregnancy, when clinically reasonable, may be a strategy to reduce this risk.
Similar(49)
As the hair grows slowly, the composition reflects a time-weighted exposure over several months, which is appropriate since long-term exposure is postulated to cause neurotoxic effects.
Since long-term relationships increase the number of exposures, the risk of transmission or acquisition of the virus also increases.
Nonetheless, the market's growth has exploded exponentially since Long-Term Capital almost went under.
That matched the lowest rate since long-term mortgages began in the 1950s.
However, since long-term survival after esophagectomy alone is unusual, clinical trials designed to identify effective therapeutic regimens are essential.
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