Sentence examples for since linkage from inspiring English sources

Our knowledge about genetics in primary headache disorders has improved rapidly since linkage was first demonstrated in familial hemiplegic migraine at the International Headache Society congress in Paris 1993 [34].

Since linkage effects may extend up to 20 cM [28], we also considered linkage results within 20 cM of previously characterized candidate genes as possible replications.

Admittedly, since linkage analysis produced a broad QTL spanning hundreds of genes, it cannot be assumed that a single gene under this QTL is influencing the activity of these drugs.

Since linkage disequilibrium may vary in different populations, this is an important source of inconsistency.

Since linkage disequilibrium is lower in this last generation, resolution should be higher when using this smaller dataset.

Since linkage disequilibrium of markers and causal variants is not complete, marker-based QTL mapping and evaluation are consequently not maximally efficient [ 1, 2].

Since the linkage is operated by two driving cranks independently then the linkage can produce a wide variety of motions for the two coupler links.

Since this linkage succeeded in maintaining the original position of the hit compound, the obtained compound exhibited highly improved potency in an in vitro assay.

Furthermore, since the linkage of microhabitats is an important factor affecting the reproduction of marine organisms in coastal areas, an understanding of the food web in each microhabitat is essential to establish sustainable fisheries management practices.

The second correction (ST) adjusted for the total SNPs (10,012) and the six tests outlined above (pST α = 0.05/10012×6 = 8.3×10−7); however this correction is likely overly conservative since prevalent linkage disequilibrium between adjacent SNPs means loci are not independent.

Further, it is unlikely that two other disease-causing genes, LDB3 (encoding Cypher/ZASP) and DTNA (encoding α-dystrobrevin), contribute to noncompaction observed in family DU-11 since no linkage was found with either of these loci.