Out of 167 patients in remission 136 (81.4%) received simultaneous immunosuppressive regimen.
And "augmentative" in this study means either combination of rTMS and stable antidepressant treatment or simultaneous association of medication regimen and rTMS.
To assess potential synergistic interactions, the treatment regimen involved simultaneous treatment of cells with LLL12 and doxorubicin for 24 hours, in addition to controls consisting of cells treated with the individual compounds alone for 24 hours.
The neoadjuvant regimen consisted of simultaneous radiotherapy/chemotherapy. External-beam radiotherapy was delivered using a two-opposed-field technique with 10 or 15 MV photons (Siemens Mevatron KD-2) at 2 Gy per fraction per day, five fractions per week, up to the year 2000.
Various strategies might be considered to improve current chemotherapy regimens, such as simultaneous use of chemotherapy and antiviral agents, addition of a proteasome inhibitor or other agent to overcome NFκB-induced chemotherapy resistance [35], [36], or p53 inactivation in tumor cells [37].
The optimal schedule of treatment (for example, simultaneous, sequential or syncopated TKI regimens) for treatment of patients with concomitant PV/CML is still unclear, but can potentially be guided by molecular monitoring and biologic correlative analyses.
The MACH-NC meta-analysis included 50 studies on simultaneous chemoradiation regardless of the employed chemotherapy regimen and radiation dose.
As a result, the regimen of HBO in combination with simultaneous radiotherapy has not been used as a standard treatment for malignant tumours.
Multiple drug resistance is often attributed to sequential functional monotherapy, and standard initial treatment regimens have therefore been designed to include simultaneous use of four different antibiotics.
It could also be shown in various randomised trials that simultaneous platinum-based radio-chemotherapy is significantly superior to sequential regimen [ 3- 5].
