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To tackle this issue, an alternative approach is being adopted to study simultaneous interactions of small molecules with multiple specific targets, also known as polypharmacology.
The performance of a bioreactor landfill is highly influenced by the simultaneous interactions of several coupled processes that occur within the landfill.
Although alcohol tolerance in yeast is a complex trait affected by simultaneous interactions of many genes, our results using a genomic library reveal potential target genes for better understanding and possible engineering of metabolic pathways underlying alcohol tolerance phenotypes.
While performing the simulations of thermal conductivity, fluid is initially considered to be at still condition and constant temperature of 300 K. Motion of fluid and change in fluid temperatures occur due to simultaneous interactions of particle dispersion and particle heat transport with the fluid medium.
This law is only valid for low "concentrations" (e.g., in chemistry, dilute solutions), where simultaneous interactions of three or more individuals have negligible probability.
Additional molecular diversity can arise when accounting for potential simultaneous interactions of receptor tails with multiple cytoplasmic adaptors.
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By combining BiFC with either FRET or BRET, it is theoretically possible to demonstrate the simultaneous interaction of three or more interacting partners.
Results for the simultaneous interaction of imperfections and energy barriers for spherical shells under external pressure will be presented.
A realistic scenario, with dissolution at low pH and subsequent increase of the pH would involve simultaneous interaction of the dissolved components.
However, BIR1-2-3 was more prone to Smac antagonism due to simultaneous interaction of two BIR domains from XIAP with two N-terminal binding sites of Smac.
The implication of these results on grinding of brittle materials, where material removal occurs due to simultaneous interaction of several grits is discussed.
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