Sentence examples for simultaneous dosing from inspiring English sources

Simultaneous dosing and DTX followed by PAK1 inhibitor treatment were most efficacious (** P  < 0.001).

The effect of low-dose prednisolone was not altered by simultaneous dosing with 300 mg/kg dipyridamole, suggesting no enhancement of the effect of prednisolone in hepatocytes.

Sequential and simultaneous dosing modalities were investigated and the annexin V/propidium iodide assay, in concert with fluorescence microscopy, was employed to visualize cells undergoing apoptosis.

The regorafenib dosing regimen in this study was selected to reduce the risk of toxic effects and drug interactions by moderating the total monthly regorafenib dose and avoiding simultaneous dosing of regorafenib and chemotherapy, especially since regorafenib has two active metabolites (M2 and M5) with half-lives of 25 (regorafenib), 26 28 (M2), and 51 64 h (M5) [ 12].

All combinations were well tolerated, but simultaneous dosing led to more body weight loss (maximum 8.3% (35 mg kg−1 CPT-11+15 CPT-11+15R5944)) than sequential dosing (mgximum 5.2% (35 mg kg−1 CPT-11+10 mg kg−1 XR5944)) or single agenthansequentialmum 5.9% (23 mg kg−1 CPT-11)).

The hope is the cocktail will produce an army of primed T-cells.Checkpoint, counterpointSome, maybe many, of the patients who do not respond to checkpoint blockers at the moment might do better if they were given a simultaneous dose of T-cells that already recognised the enemy.

We are confident this system can be used to expose in vitro ALI cultures to eight independent and simultaneous doses of whole smoke knowing that smoke delivery, dilution precision, and chamber dose are reproducible and expected.

With a simultaneous dose escalation and schedule acceleration it is indeed possible to take maximum advantage of G-CSF activity and to increase CDE dose intensity by a factor 1.65-1.80 for a maximum of 3-4 courses.

The fractionation schemes used were 28 × 1.8 Gy to the whole breast, and with a simultaneous dose of 2.3 or 2.4 Gy to the tumour bed (total dose 64.4 or 67.2 Gy).

The other three patients received combinations of pressor drugs at various times during their stays; Patient 5 received simultaneous doses of three drugs for the first part of his stay.

5) In severely toxic patients, a simultaneous intramuscular dose of 60 mg of Artesunate on each buttock followed by a daily dose of 60 mg for the next 5 days reduces the parasite load as it is relatively new and thereby less resistant and is an effective schizonticide.