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However, Bruck et al. [ 34] estimated a subset of 31 parameters to fit the model to data from all conditions they simulated and did not present simulations without the gene expression data, preventing an assessment of the contribution of gene expression changes.
Then, we further perform some MD simulations without the movement constraint of graphene in the y direction to better match the real experimental conditions.
The results showed that the production performance calculated from the numerical simulations without the input of relative permeability functions was almost the same as the experimental data.
Backwards-differencing time-integration, coupled with an underlying Newton Krylov nonlinear solver (SUNDIALS-CVODE), is found to substantially accelerate simulations, without the typical requirement of preconditioning.
In our simulations, without the loss of generality, the number of arriving VNs is randomly distributed from 1 to 4, and each VN randomly consists of 3 or 4 nodes.
The validated model was used to develop correlations that can be implemented in a BESP, allowing users to take advantage of the accuracy gained from CFD simulations without the required computation time.
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In the simulations without control, the value of the linear mode to the nonlinear deflection is quantified; and the minimum number of linear modes needed for accurate model is obtained.
However, for the other processes p21 expression levels were significantly lower compared to the simulations without considering the cooperative effect of the miRNAs.
The physics of these models are simplified through approximations that enable more efficient simulations, without compromising the accuracy of the relative comparisons between implant designs or configurations.
With it, configuration parameters can be altered for new simulations without recompiling the entire simulator code.
In both cases, we carried simulations without coupling the mechanics and with coupled mechanics to assess the effects of tissue deformation on electrophysiological metrics.
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