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Simulations were run with each of these networks using the Bionet simulator [ 26].
Most simulations were run with m>2.
All simulations were run for 2 μs.
All the simulations were run with in-house codes.
Some simulations were run to validate the model.
Simulations were run for a maximum of 3.2 ka.
Simulations were run for three different transient load profiles.
The simulations were run for 400 ps using an integration time step of 0.2 fs.
Simulations were run for two set-ups: with and without VHH nanobody.
The molecular simulations were run using a modified version of Gromacs 4.0.551.
These MD simulations were run with the NAMD 2.9 software package38.
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