Sentence examples for simulations of trials from inspiring English sources

Simulations of trials with either the prespecified number of events (350) or the observed one (372) indicated that no dose below the reference dose of 1,250 mg/m capecitabine had 80% power to show noninferiority to the reference dose level (power ranging from 61% for 850 mg/m to 72% for 1,000 mg/m).

Based on a series of meta-analyses of cohorts and clinical trials and simulations of trial designs and analytic methods, the workshop concluded that a confirmed decline in estimated GFR of 30% over 2 to 3 years may be an acceptable surrogate end point in some circumstances, but the pattern of treatment effects on GFR must be examined, specifically acute effects on estimated GFR.

Power of the test was evaluated through simulation of trials.

Once basic commands are supported, an engine will be incorporated that orchestrates the execution of complex modeling workflows, involving simulation of trial designs, parameter estimation, derivation of inferences, and analysis reporting.

Substantial increases in power resulted when including only participants positive for three or more biomarkers in simulations of clinical trials.

Simulations of mating trials performed in the context of sibling analysis indicate that the heritability of sperm competitive ability is dramatically underestimated when fertilization success values are used.

Here I perform simulations of mating trials performed in the context of sibling analysis to investigate whether the ability to detect additive genetic variance underlying the sperm competitiveness phenotype is hindered by the relative nature of fertilization success measurements.

In each step of the simulation, a number of trials was simulated.

The accuracy of the Archimedes Model is verified using a variety of techniques, most importantly the simulation of clinical trials, comparing the model's results with the observations from the trials.

14 Meta-simulation of clinical trials using observational patient records represents a novel approach to clinical trial simulation.

Computer simulation of randomised trials demonstrated 92% confidence that the simulated NNT was within ± 0.5 of the underlying value of 2.2 with this number of patients.