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Moreover, the simulations, in the first two columns of Figure 7, also showed that the presence of SORLA in the TGN decreases the total amount of free APP, and increases the total amount of used APP.
In its recent report on this topic, the Royal Society specifically includes computational models and simulations in the first recommendation which states that " Scientists should communicate the data they collect and the models they create, to allow free and open access, and in ways that are intelligible, assessable, and usable for other specialists in the field wherever they are in the world".
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All of the simulations in the second example considered the condition of rank of X greater than 1.
The simulations are all evidently in steady state, and they reached this state (at least for the particles) very soon after the beginning of the simulation (in the first year of simulated time).
This study considered three scenarios for simulation: In the first scenario, STA node request video stream from the server, but mobile mesh nodes just relay the received packets.
In the mathematical simulation, in the first step, experimental data is reproduced and subsequently, the model can be used to predict the behaviour of the system.
The simulations begin in the first generation after a point mutation arises in the population.
Users can use our automated mutant structure modeling and ligand docking simulation services in the first two options (Fig. 3).
As illustrated in Supplementary Figure 1(a), the interaction of Tyr233 and Cys24 and the concomitant protein conformational changes observed in the initial apo simulation were essentially repeated in the second apo simulation, however, as in the first simulations, did not occur in the second covalently ligand-bound simulation.
It reviews selected experimental studies of airslides with the goal of identifying characteristic features of these flows that we attempt to model in the numerical simulations described in the second companion paper.
However, the most popular inhibitor conformation (Cluster 1) of the first-round simulations disappeared in the second-round, suggesting that AHP adopts only one conformation in the BoNTAe active site.
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