A detailed understanding of the interaction between ligands and receptors, using molecular docking simulations, constitutes the very basis of RDD [ 10].
However, the good agreement between our theoretical calculations and the experimental results obtained for the fabricated switch confirms that our simulations constitute a good prediction of the device's experimental performance.
These simulations constitute a challenge due to the strong discontinuity of electromagnetic material properties involved, the relative low field value within the dish cultures compared with the rest of the domain, and the presence of the meniscus shape developed at the liquid boundary.
In order to evaluate the information content of these reflections, Monte Carlo simulations constitute a well suited approach, since tissue model and thickness are given as a known ground truth.
It has been claimed that computer simulations constitute a genuinely new methodology of science or even a new scientific paradigm, which, moreover also raise a new host of philosophical issues (Humphreys 2004, 2009, Rohrlich 1991, Winsberg 2001 and 2003, and various contributions to Sismondo and Gissis 1999).
It can also be combined with the dynamic simulation tests to constitute the simulation test platform with more thorough functions and reduce the development cost and time of dynamic test system [21, 22].
The inorganic component of the simulations constituted of a (1,-1,1) candite and a (1,1,1) α-quartz surface.
Compared to the state-of-the-art approaches, this methodology includes the assessment of the uncertainty by means of Monte Carlo simulations, constituting a valuable step forward.
In other words, our ensemble of simulations constitutes a probabilistic sensitivity analysis (PSA) on natural history parameters of influenza as well as on the variability of influenza seasons.
In the following sections, the elements that constitute the simulation tool are described.
