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Exact(22)
Consequently the use of models and simulations are useful.
Directed evolution can be used to enhance function and stability, while more advanced computational techniques and physics-based simulations are useful at elucidating structural flaws and at guiding the design process.
Molecular dynamics simulations are useful methods for investigating the nanoscale structure and properties because they give us the trajectory of each atom.
Simulations are useful when you know how parts of the system work and want to generate data about the system as a whole.
Molecular dynamics (MD) simulations are useful tools for structure-based drug design.
The results from the scenario simulations are useful for a relative comparison of properties.
Similar(38)
Although the high charge density of a 100% POPS bilayer does not reflect the in vivo environment of FK1TMD, these simulations were useful in determining the effect of anionic lipid headgroups, as we could compare directly with our simulations of FK1TMD in POPC.
The results from the simulation are useful as a guide for further system design and testing.
Whereas detailed results of coupled simulation are useful here for engineers, global performance indicators defined in this study give useful hints for stakeholders and urban cooling strategy design.
For example, the functionality of a pathway and the status of a dynamic simulation are useful in gaining an overall understanding of the pathway.
While much more detailed modeling studies are required for realistic drug target testing, analysis of regulatory networks through simple model simulation are useful for assessing the disease mechanism and possibly more precise treatment options by targeting key parts of a complex pathway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com