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Each simulation was initiated with maximal diversity (initial genotypes randomly drawn from all possible allelic states) and run for successive generations until the mean within-population expected heterozygosity (HE) reached 0.8 (comparable to levels found in many studies of natural populations using microsatellites).
Each replicate simulation was initiated with 100 individuals.
Each simulation was initiated with a single cell starting with a DM count equal to 1 at time zero.
A simulation was initiated from the crystal structure of ecRNH in the Mg 2+-bound state (PDB ID 1RDD).
Each simulation was initiated with the χ1 angle of the Ser sidechain in one of the three possible stable rotamers.
The RMD simulation was initiated by using unambiguous NMR distant constraints on the peptide without the presence of the disulfide bond.
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A general SP simulation model was initiated, in which polymer viscosity dependence on concentration and salinity was established in the laboratory; surfactant phase behavior parameters were generated from test-tube results; and oil desaturation was based on additional coreflooding.
Both the kcat and standard deviation for each enzymatic reaction occurring in solution are selected before the simulation is initiated.
The simulation is initiated by first finding the equilibrium given a constant amount of free neurotransmitter at 500 nM and then goes on for a transitory time of 5 seconds at the predetermined tonic firing rate.
The simulations were initiated in a cubic cell universe and run in explicit solvent, with the wild-type and variant proteases in the fully closed conformation and under periodic boundary conditions.
To explore the intracellular permeation pathway, two independent SMD simulations were initiated from S1,S2-DAT.
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CEO of Professional Science Editing for Scientists @ prosciediting.com