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The mitochondrial oscillator model has been validated by extensive simulation of reported experimental evidence, and experimental verification of specific model predictions [18], [46].
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The validation of the simulation model shows good agreement of reported and calculated values for species concentration and temperature development in time.
The current simulations imitate the distributional properties of reported exposure traces from different repetitive occupational tasks.
Optimal study design simulations of previously reported clinical data demonstrated that a 0 48-hour collection was an accurate surrogate of total systemic exposure (AUC0 48-hourr warfarin.
Similar to the results of simulations reported in the literature, the simulations presented here, in which sodium ions diffuse freely from the bulk to the interior of the δ-OR, μ-OR, or κ-OR bundles, show that sodium always enters the receptor from the extracellular milieu and reaches the allosteric site seen crystallographically quite rapidly (nanosecond time scale), following similar pathways.
A series of simulations reported in the following section of this paper assume constant age-specific incidence in order to explore the impact of cohort effects.
The results of this simulation are reported in Figure 6, which shows the evolution in time of the population of cells, and shows how the cells redistribute among the sepal, petal, stamen, and carpel attractors.
This article explores the history of simulation, reports the results of a modified systematic review of currently available systems and performance, and identifies the gaps in current research and development.
Compared with other forms of simulation, however, the reported use of VPs within nursing is limited.
The results of numerical simulation are reported to validate the proposed design.
All seven of the simulation studies reported a cost advantage for novel antipsychotics for specific patient populations under certain conditions.
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