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Here we combine finite element simulation of oxygen transport and quantitative comparative analysis of cellular microenvironments to elucidate the critical variables that promote reproducible intestinal organoid contraction.
Experimental results are compared with the results of computer simulation of oxygen reduction proposed by Adanuvor [J. electrochem. Soc.131, 2095 (1990)].
The model provided a good simulation of oxygen, carbon and nutrient dynamics in the systems; primary production (by benthic microalgae and phytoplankton); and biomass change of important faunal groups (crabs and gastropods).
Rogers, B, Fair, RB, Dyson, W, and Rozgony, GA. "COMPUTER SIMULATION OF OXYGEN PRECIPITATION AND DENUDED ZONE FORMATION". Electrochemical Society Extended Abstracts 84-1 (December 1, 1984): 54-54A.
Rogers, B, Fair, RB, Dyson, W, and Rozgonyi, GA. "COMPUTER SIMULATION OF OXYGEN PRECIPITATION AND DENUDED ZONE FORMATION". Proceedings the Electrochemical Society 84-7 (December 1, 1984): 74-84.
Information regarding the circuit design of oxygen sensing system, the cell culture, the cell extraction of Actinomyces viscosus, the simulation of oxygen gradient generation, and bulk culture of murine embryonic fibroblast cells under different oxygen conditions, including referenced literature.
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Simulation of oxygen-18 process is executed by Hysys software, and the required inputs and outputs for inventory of life cycle were acquired.
Global simulations of oxygen and carbon transport in the improved furnace showed that the carbon concentration in the crystal can be reduced to a negligible value in the order of 1014 atom/cm3; simultaneously, the oxygen concentration in the crystal can also be reduced by at least 30%.
We verify the model by first showing that it is an improvement and able to reproduce what the spherical model describes, and then testing it against the average oxygen reductions directly calculated from pore-scale simulations of oxygen diffusion and reaction in the two catalyst layers.
This approach was used in the steered MD simulations of oxygen diffusion in a monolayer of hexadecane and cholesterol molecules, with one end constrained by a harmonic potential to imitate the headgroup attachment.
To confirm this viewpoint, effective oxygen diffusion coefficients (De,s) of scaffolds were deduced from experimental measurements and simulations of oxygen-concentration profiles were performed using these De,s values in a two-dimensional (2-D) perfusion model.
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