The model is validated by simulation studies of known mutant plants.
The model is validated by simulation studies of known experimental overexpression data from SH-SY5Y cells and the unknown model parameters are estimated either computationally or by experimental fitting.
We use the sediment flux in the flow boundary zone and the grain-size distribution of the Lagrangian particles as proxies of the deposit features, and by these parameters we qualitatively compare simulations with deposits of known eruptions.
In this work the authors investigate a complex application in which the braking and traction systems are tested using a full scale roller rig able to perform the simulation of a known wheel rail adhesion pattern (especially degraded adhesion) applying a HIL (Hardware In the Loop) approach.
While clearly, no two hurricane wind fields are the same, the simulation of a known storm provides some basis for comparison, given the approximations needed to make a hindcast, which are amplified when making a forecast.
Simulation has the advantage of known true parameter values, as well as presenting the possibility of manipulating the total effect of the covariate and the magnitude of the difference between the within-cluster and contextual effects.
Generally, in simulation and modeling, the number of known parameters is less than that of the unknown ones.
Furthermore the results suggest a need for careful and thorough evaluation of the tools used in a particular analysis pipeline by simulation and analysis of data of known constitution.
All the spectra exhibited a mixture of free radicals, the absolute spin concentration of which was obtained from EPR signal simulations and intensity calibration using references of known spin concentrations.
Simulations of the known regulatory elements of the IL-2 pathway (Feinerman et al., 2010) predict a low saturating threshold and a strong population size dependence for IL-2 output.
