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However, the Gillespie stochastic simulation framework allows us to incorporate reversible reactions if we know the forward and backward reaction rates [ 15].
While the selection coefficient conflates these parameters into a single number, our simulation framework allows these parameters to be separated and investigated independently.
Our LSM simulation framework allows us to determine how these forces are distributed along the cell to generate the resulting cell shapes, both for wild type and mutants.
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Additionally, our simulation framework allowed us to quantify the increase in power due to bidirectional selection.
All in all, the combination of the ABC formulation with these different beam element variants (i.e. the torsion-free element, the Kirchhoff Love element and the Simo Reissner element) results in a very flexible and modular simulation framework that allows to choose the optimal element formulation for any given application in terms of accuracy, efficiency and robustness.
We investigate the relation between throughput, volume-based user behavior and traffic dynamics with a simulation framework which allows the efficient modeling of large UMTS networks with both HSDPA and Release '99 users.
The first goal of this investigation was to develop a widely-configurable discrete-event simulation framework that allows for quantification of long-term patient flow outcomes.
Updating climate impact simulations in the presented rigorous replication framework allows analysing specific new information in the latest generation climate model data as well as crystallizing essential expectable patterns of change that need to be addressed in adaptation strategies.
Simulation studies indicate that the universal demosaicking framework allows for cost-effective camera image processing and produces visually pleasing full-color digital images.
The use of a plug-in-based modeling and simulation framework has allowed a rapid prototyping of a suitable modeling and simulation environment for our experiments.
We have developed and integrated several models into an overarching simulation framework that allowed early assessment of toxicity, efficacy, and cost effectiveness in CRPC patients treated with eribulin.
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