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The conclusions are that evidence regarding in-situ simulation efficacy is still emerging and that practical programme planning strategies are needed [ 21].
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Educated at Yale, he talked about simulation methodology efficacy rather than the consequence of a hit-and-run.
The intensive simulations demonstrate efficacy of the proposed HOSM and SMC-SMDO control algorithms for launch vehicle attitude control.
Based on all of the mentioned simulations, the efficacy of hybrid switching predictive controller with bi-level ELM (HSPC-BELM) is verified.
The results of the simulation experiments show efficacy, generality and applicability of the proposed control methodology.
Nevertheless, simulation of the efficacy test conditions as close as possible in the validation process is preferred.
Through Monte Carlo simulation studies, the efficacy of SMA vs. LMM and traditional UMA, under different types of covariance structures, was illustrated.
Our study deepens understanding of this area, by demonstrating that contextualisation of interactive prescribing workshops through embedding them in an extended simulation enhances their efficacy still further.
As shown in Figure 9, in BT474, the simulation based predicted efficacy of erlotinib alone to counteract RPS6 (Table 3) was not as convincing as in case of drug combinations.
However, to our knowledge, the current analysis is the first example of a simulation framework for efficacy evaluation that integrated dose reductions in a somewhat more explicit and mechanistic fashion, potentially allowing more flexible use when evaluating alternative scenarios.
A recently published update of this evaluation [ 74] showed mean cost savings of €4991 per patient discharged alive or €1047 per patient admitted to the hospital using the same simulation model including efficacy data derived from the meta-analysis by Bollhalder et al. [ 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com