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PolyCAD allows any type of X-ray source to be used: an X-ray tube of finite beam dimensions or an astrophysical object can be simulated in combination with the polycapillary optics.
These two alternative demographic scenarios were simulated in combination with the three selection hypotheses gcc, cal and lbk (see below).
Hypothetical drugs with molecular weights of 100, 200, 500, 800, and 1,000 g/mol were simulated in combination with log P values of 0.01, 1, and 5.5.
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Different interventions, namely school closure and antiviral strategies, were simulated in isolation and in combination to form different plausible scenarios.
Fifteen strains with complete genome sequences were simulated in all possible combinations.
The sequential inclusion of up to eleven strains (eleven columns in a pan-genome matrix) was simulated in all possible combinations (N = 11!/ [ n-1)!*(11-n)!]).
In the sensitivity analyses we compared all policy-strategy combinations simulated in the base case analysis for five different scenarios that represent contrasting real life situations (table 3).
The input signals were simulated in terms of different combinations of these specifications, and their effects on signal integration by DARPP-32 without or with perturbations were systematically evaluated.
The power plant was simulated in two steps with different combinations; while "Therminol VP I" was used in the first step, as heat transfer fluid, in the second step, "Therminol VPI" was replaced by "Molten Salt".
In the present study we used the model of simulated in vitro ischemia, i.e. combination of glucose-free anoxia with extracellular acidosis (pH 6.4), which was characterized previously in details for endothelial cells and cardiomyocytes [ 11, 20, 21].
Assuming that an influenza pandemic occurs every 30 years on average, and that pre-pandemic vaccines are at least 30% effective, a pre-emptive vaccination strategy is more effective, less costly, and more cost effective in terms of cost per life year saved than a reactive vaccination strategy, for all severities and combinations of interventions simulated in this study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com