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Having simulated a reference panel, we then simulated a GWAS dataset as the target for imputation.
We also simulated a reference database that has intermediate levels of most taxa.
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Solar simulators generate radiation which should simulate a defined "reference sun" as perfectly as possible, and most important is the fitting to the spectral distribution.
Similar results were seen when we simulated an early-stage reference by splitting the GRCm38/mm10 genome into a scaffold of the 403 chromosomal Giemsa bands (based on coordinates from the UCSC genome browser [ 28]), and realigned our libraries to this new reference version (see Additional file 5: Figure S4).
The properties of the residual generators are experimentally investigated and verified by simulating a general aircraft reference trajectory.
We simulated an optical map using the reference genome for F. tularensis and loblolly pine since there is no publicly available one for these genomes.
The framework currently makes it available agent models for conventional, cooperative and clustered CDN architectures that have been simulated according to a reference simulation scenario.
Note that the work flow can either be started with simulated data from a reference model or with real data.
Optimal sequences are localised at the minima of a sequence-structure energy landscape defined using a complex scoring function (an all-atom molecular mechanics force field plus statistical terms including entropy and solvation) measured with respect to a reference state simulating a denatured protein.
We explored the long-term health benefits of the interventions by comparing simulated outcomes for a reference cohort and an intervention cohort.
In contrast to simulations without gene expression data, which by construction simulated the reference condition and had a normalized SSE of 1.0, predictions using gene expression were closer to the experimental values of the treatment conditions.
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