Sentence examples for simulate trial from inspiring English sources
In the same way that variances can be appropriately scaled according to sample size during model fitting, variances were scaled during simulation to simulate trial arms of different sizes.
The predictive performance of the GAM to simulate trial outcomes was also successful as evaluated by a visual predictive check and where the trial simulations accounted for both the parameter uncertainty (from 1,000 bootstraps) as well as the residual error (data not shown).
We propose using data from a previous trial to formulate assumptions that can be used to simulate trials and thus improve the design of new trials.
As they do not include any stochastic component, they cannot simulate trial-to-trial variability.
This is a minor issue as the model can estimate and simulate trials with >500 patients in around 3 4 h.
We simulate trials under these forecasts and test potential start dates and rollout schemes to assess power to detect efficacy, and bias in vaccine efficacy estimates that may be introduced.
We illustrate this study design through a simulated trial example, and we investigate the operating characteristics using simulation studies.
To demonstrate the effectiveness of the proposed method, it is applied to a simulated trial stranding scenario.
The model exhibits theta band oscillation, especially among the non-5-HT inhibitory neurons during the rewarding outcome of a simulated trial, thus forming a model prediction.
The sample size for each simulated trial was 50,000.
Group sizes were equal in each simulated trial.
