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Using mutational analysis, we successfully refined the CCR to amino acids 183-189 or 192-194, however it remained unclear whether these residues corresponded to the cleavage site or if they simply affected cleavage by another means.
Distinguishing between genes that are truly expressed differently and genes that are simply affected by various sources of noise remains a challenge.
However, if the Ser667Phe mutation simply affected the affinity of the mutant band 3 for GPA, then a titration of GPA with S667F-B3 would be expected to show a linear relationship.
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It was an image that, rather than simply affecting him, branded him.
"The changes will simply affect taxes paid on future super earnings, and entitlements to make future contributions to super".
He added: "These members have done great harm to the Olympic ideal, now the greatest service to the Olympic movement is for them to simply affect their fate.
Freddie Mac has said repeatedly, and emphasized again yesterday, that the restatement has no impact on the actual results of its business last year, and simply affects when the profits it made in 2002 are reported.
We have had 10 years of debate about when drugs like Prozac are used to treat illness and when they are simply affecting personality traits, like pessimism, shyness and low self-esteem.
The flaw in the theory became apparent as soon as it was proved, once and for all, that irresponsible behaviour in a market did not simply affect the parties involved but could also, thanks to the knock-on effects of modern derivatives, bring whole national economies to their knees.
"From Ashes of Yukos, New Russian Oil Giant Emerges" (news article, March 27), about the politically motivated expropriation of Yukos and the current rigged "sale" of its assets, did not mention that the renationalization of the company sanctioned by President Vladimir V. Putin did not simply affect the company's now-imprisoned billionaire chief executive, Mikhail B. Khodorkovsky.
The latter assumption simply affects the stoichiometric coefficient of "vapor" (H2O in the present exercise) in the reaction set.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com