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However, this simplistic observation does not explain the fact that the highly prevalent H9N2 strains in Eurasia and the Middle East have α2,6SA humanlike receptor specificity (5) but have yet to cause a pandemic, despite serological evidence showing considerable human exposure to these viruses.
However, the reality beyond such a simplistic observation is much more complex.
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Peter Buffett's New York Times Op-Ed piece "The Charitable-Industrial Complex" reads like the diary of an early explorer, a mix of insightful and simplistic observations of the new world he's been thrust into as co-Chair of the NoVo Foundation: the wild territory at the intersection of money, politics, and highly-complex societal problems.
After rebutting one critique after the other, however, Acocella, a staff writer for The New Yorker, offers little aside from persuasively argued but simplistic or derivative observations regarding the symbolism and the "tragic sense of life" in Cather's novels.
A simplistic explanation for this observation is increased uptake by the iron starved brain tissue, reducing levels of Tf in the brain interstitial fluid and CSF that form a common compartment.
This phenomenon of "population shuffling" has been suggested based on ubiquitin (Smith et al, 2015) and is also consistent with the observation that simplistic model of clashes in CypA cannot classify two distinct states (van den Bedem et al, 2013).
From a rather simplistic point of view, the observation that several different mechanisms of drug resistance exhibit a common theme of epigenetic regulation indicates that future studies analyzing the significance of cancer-specific miRNA-mediated chromatin remodeling may identify novel targets for therapeutic intervention.
These observations challenge the more simplistic Warburg effect models and suggest that the coordination of glycolysis and mitochondrial pathways is important for tumor growth.
At first, these observations may sound flip and simplistic, until you begin to discern the wisdom behind them.
Several observations, however, argue against a simplistic interpretation.
However, I find the observation itself unsurprising and the analysis simplistic and limited in scope.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com