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Although the generation of nucleotides may not be simple, the essence of Life is our genome which is based on nucleotides and would therefore represent the starting point.
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However, this simple description contains the essence of the process.
Alternative and more complicated models exist (e.g., VanBuren et al., 2005; Margolin et al., 2012), but this relatively simple one captures the essence of the biochemistry that the microtubule end presents a mix of high and low affinity binding sites, depending on neighbor context in a reasonable way and using a small number of adjustable parameters ('Materials and methods').
As William Friedkin, the director of "The Exorcist," observed 27 years after Linda Blair's head spun 360°, horror movies, like Hitler, pose a chilling, unanswerable question: "Why do bad things happen to good people?" The horror director Brian De Palma once described the simple essence of his genre: "There is just something about a woman and a knife".
Theologians in this school engaged in a century-long "quest for the historical Jesus," in which they sought the simple essence of Christianity.
"It was an investigation: Who are we, and how did we become the way we are?" The text of the book starts with a simple but telling declaration — "The essence of a portrait has more to do with enigma than with certainty" — and this conflict between seeing and not seeing emerges gradually throughout.
This simple model hence captures the essence of lateral and thickening growth behaviour in polymer crystallisation.
Though the brainstem seems simple, the model includes the essence of the resolution of conflicts between multiple values.
In particular, we propose a simple model that captures the essence of tree aggregation in such heterogeneous sensor networks.
This simple, linear logic was the essence of the human resources policy of the government right through the Suharto era.
But the key to their lasting success is pretty simple: in essence, the boot's design hasn't changed since the '70s even though it was co-opted by generation Y's hip-hop community, who made it their own.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com