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IBS and weighted IBS kernels can be regarded as sums of simple similarities evaluated at each individual SNP, which, however, may result in loss of power when complex interactions dominate the genetic effect of the SNP set.
Similar(59)
The fold-changes for the various similar sample sets (e.g., exercised rodents) were averaged and a simple similarity scoring scheme applied based on the numbers of genes with same-direction alteration (fold change at least 1.5) between each pairwise disease condition comparison.
CRV score is not a simple similarity measure.
Although investigations have shown that simple similarity d s s is comparable to random prioritization, XACML similarity enabled significant improvements compared to simple similarity and random prioritization.
This type of information represents nominal features and enables the use of simple similarity functions.
Simple similarity searching with known ligands can also be effective [20, 21].
The authors compare the proposed approach with simple similarity and random prioritization using the APFD metric.
His other society making bond, the mechanical solidarity of simple similarity, creates fractious groups.
The second case study tests if we can use charges and a simple similarity-based model to predict pKa.
Although 2D fingerprints are simple similarity methods, some have been found to have a significant scaffold-hopping potential [39, 40].
Using such fingerprints, the similarity between two molecules can be calculated in a straightforward manner with simple similarity metrics such as Tanimoto [1], Dice [2], and so on.
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