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The truth might be that there is no simple ointment for this one.
The first group was treated with simple ointment, and served as a negative control.
Particularly, the resin showed significant (p < 0.05) difference in tensile strength when compared to the simple ointment treated groups.
Simple ointment of the 80%% methanol extract was prepared following the formula (Table 1) described in the British Pharmacopoeia [ 25].
The wounds were treated with topical application of the oil, resin, 0.2%% nitrofurazone or simple ointment for 10 days [ 28].
Simple ointment, LJEE ointment (10%, w/w) and the reference standard drug were applied topically (dose, approximately 0.20 g/wound) once daily.
Similar(41)
a P < 0.05 and b P < 0.01 compared to the values of simple ointment-treated rats in each group, respectively.
Conversely, a high IL-6 level (93.5 ± 15.8 pg/ml) was observed on day 9 after wounding in simple ointment-treated rats.
On days 15 after wounding, the hexosamine content in the LJEE and nitrofurazone ointment-treated groups was still higher than that in the simple ointment-treatment group.
Similarly, hydroxyproline content was significantly higher in the LJEE and nitrofurazone ointment-treated groups than in the simple ointment-treated group throughout the course of healing (Table 2).
a P < 0.05 and b P < 0.01 compared to the values of simple ointment-treated rats on the indicated day in each group, respectively.
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