Sentence examples for simple loci from inspiring English sources

However, unlike a previous study that used PCR and Southern hybridization to track processing of two simple loci containing just two and three nonscrambled IESs, respectively [39], we detected no specific order of conventional DNA deletion events.

Similarity was tested by mean Euclidean distance within groups of related genera for total frequency in simple plus compound loci, repeat count in simple loci, and frequency of polymorphism in simple loci.

Motif frequency was strongly, positively correlated between compound and simple loci, although the correlation weakened for hexanucleotide motifs.

Simple loci were typically from 5 to 20% of all loci with zero or one mismatch, but at least 80% of loci were simple with two allowed mismatches.

Repeat count was not significantly correlated to frequency of simple loci, except in hexanucleotide motifs and the collective motifs that they dominated.

These frequencies are itemized for simple, compound, and total loci, and for the fraction of simple loci to simple plus compound loci, as listed in the "Type" column of each table and defined fully in the Abbreviations.

TALE fusions with effector domains offer a broad range of applications, ranging from simple locus-specific transcriptional activation and repression [ 82, 85], through direct induction of epigenetic changes on DNA [ 86] or on histones [ 87], to using them for visualization and pull-down of specific genomic loci [ 88 91].

To investigate the results at the simple locus level, we proceeded as follows: we computed the averages of each locus' methylation values across all samples for tissue and stool in each category of normal (N) and cancer (Ca) individuals; for blood, we retained the value provided by Illumina for the single pooled sample assayed.

The frog genome and the genomes of three fish species presented progressively simpler loci, although only the 7-exon structure could be identified.

Supplementary Table 15 (see Additional File 15) presents frequencies of di- and trinucleotide motifs in perfect, simple microsatellite loci reported elsewhere from 16 genera, along with the minimum lengths of the loci, for comparison with the results reported here.

How the results of these simple, 2 loci models might translate to larger epistatic networks in other contexts involving many more loci is yet unclear.