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Some veiled their frustrations behind an alleged simple affinity for law and order, but others were upset for reasons that were clearly far more personal.
But models can provide increasingly accurate predictions for a vast majority of compounds with simple affinity for, say, the 10 most promiscuous ion channels and exchangers.
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If this were the case, simple affinity of AZD9773 for the trimer may be very different to potency in cell-based assays, where binding to just one molecule in the network could result in a breakdown of that network and loss of signalling.
I also feel a simple affinity with RFK.
We have shown that DNA microarrays can resolve even subtle changes in hybridization affinity for simple target mixtures.
His friendship with Alison Krauss seems to have reignited in Plant a long-dormant affinity for the simple pleasures of family music.
In addition, if their binding affinity for this simple sequence were higher, Smad proteins would decorate entire chromosomes.
Ms. Quinlan is a model of sorts for Real Simple because, she said, "I had an affinity for the idea of simplifying your life; I did it myself".
Gam is a simpler system, a single protein with a high affinity for double stranded ends.
Strep-tag II has a strong binding affinity for an engineered streptavidin derivative called Strep-Tactin, which enables fast and simple one-step purification [34].
Lin-28 has a strong affinity for let-7, perhaps suggesting Lin-28 could prevent interaction with Drosha/DGCR8 by simple competition.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com