However, it should be also considered that deacylated GAP-43 could be a preferred substrate for proteasome degradation [43], [44], avoiding cytosolic accumulation, and/or that 2-BP not only inhibits PATs but also APT activity similarly to that observed using APT-1 inhibitors [45].
Similarly, the clinical significance of aPTs in both primary and secondary APS is still a matter of debate.
"In Vain" is programmed with Steve Reich's "Music for 18 Musicians," an apt pairing, given the similarly visceral impact of that piece.
Steven Soderbergh's "Magic Mike," made for $7 million, similarly has a physicality that's both apt to the subject and that conveys a sort of artistic self-renewal.
These difficulties result in a density function characterized by high variances, and imply that predictions from this simulation model, and similarly large fate-and-transport models, are apt to be highly uncertain.
Similarly, it is unclear why "impact" is an apt measure if the goal of research is to answer questions.
The most apt comparison may be Wes Anderson, whose films similarly feature casts of eccentrics, dialogue full of non sequiturs, deadpan humor, and unabashed farce.
The Shyamalan comparisons are apt, for the Sixth Sense director was similarly hamstrung by the huge success of his first movie (and its genuinely impressive twist ending).
Similarly, studied wells 2, 3, 4, and 7 were exposed and Apt 4 did not develop in these wells while deposition continued in wells 1, 5, and 6.
