Exact(12)
Our method relied on ligand clusters, whose members possessed similar 2D structures, rather than the exact target-ligand binary relationship [6] or similarity of functional ligand sets [7].
Metabolic Tinker [28] uses a heuristic based on similarity of functional groups of atoms and bonds between the current compound and the target compound identified using a graph comparison technique similar to the one described in [47].
4ADNT also had a relatively high similarity of functional terms with 2,4DNT and 2,6DNT (Table 5).
We first examined the similarity of functional terms from the up-regulated gene groups between compounds (Table 5).
Based on randomized simulated data sets the observed similarity of functional genes between sites is significantly greater than expected by chance for all comparisons except those involving the Antelope Island site and the 3510S site (Table S1).
The high association indicates similarity of functional constructs.
Similar(48)
"During this continual research, I noticed similarities of functional, beautiful objects and artworks that humans have made across cultures like baskets, tools, abstract designs, and the way symbols are used to mark history and tell stories," she explains.
Later, Chagoyen et al. used the pair-wise similarities of functional annotations from GO to calculate the coherence score of a protein set.
Repeated similarities of functional annotations were noticed, particularly for genes involved in immune response, ATP metabolism and detoxification.
The similarity of all functional genes is significantly higher than that of 16S genes, indicating higher dispersal for all functional gene groups analyzed.
Functional relatedness of genomes is a measure of similarity between two genomes based on the similarity of the functional annotation of genes.
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