Sentence examples for similarity methods from inspiring English sources

Note that 2-D similarity methods do not always recognize structural similarity between biologically similar molecules that 3-D similarity methods readily do [8, 10, 11, 14, 41 44].

All molecular similarity methods exploit the so-called similarity principle, which states that "structurally similar molecules are likely to have similar biological and pharmacological properties" [51].

Table 3 Mean performance of similarity methods.

Table 5 Mean difference in performance of similarity methods.

However, traditional 2-D similarity methods sometimes fail to recognize structural similarity that can be easily realized with three-dimensional (3-D) similarity methods [13 16].

We evaluated the use of document similarity methods to identify unreported links between ClinicalTrials.gov and PubMed.

This enables an isolated view on the effects of the similarity methods used for the rankings.

Table 6 Mean difference in performance of similarity methods across MUV data sets.

Fingerprint based similarity methods generate fingerprints by systematically recording patterns present in compounds.

Table 4 Mean performance of similarity methods across MUV data sets.

Performance of individual chemical similarity methods on hypothetical libraries of linear peptides.