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Each utility is different, but similarities were made to see the application can distinguish the differences.
Presence of multiple transmembrane domains was predicted using TMHMM server v2.0 (http://www.cbs.dtu.dk/services/TMHMM/). Multiple alignments and calculation of sequence identities and similarities were made using GeneDoc software (http://www.nrbsc.org/gfx/genedoc/ebinet.htm).htm
Similar(58)
Sequencing results were analyzed using the BioEdit sequence alignment editor (Ibis Biosciences); primer sequences were removed and nucleotide similarity comparisons were made using the GenBank database.
In the case of the intersession similarity, comparisons were made between the first and last session during which the neuron was successfully isolated.
Similarity searches were made using BLASTP [41] against NCBI databases and genome sequence protein databases [42], [43]; www.jgi.doe.gov/genome-projects/).
The similarity plots were made with both DNA and protein sequences of the extended M20L TPX2 domain to check the quality of conservation.
Computer-aided sequence similarity searches were made with the BLAST suite of programs at the National Centre for Biotechnology Information (NCBI; ) Motif searches were made using PROSITE, TMPRED, Signal IP and PSORT II.
Analyses of similarity (ANOSIM) [81] comparisons were made using the one-way ANOSIM function in the PAST software package [82] to detect differences in the ant diversity of different strata.
For activity cliffs defined on the basis of calculated (molecular fingerprint-based) similarity values, comparable observations were made.
One Twitter user compared it to a "sack of spuds tied in the middle," another said that it had the look of a "fire retardant bin liner" and frequent references were made to similarities with jumpsuits worn by mechanics.
Manual inspections were made when similarities were weak.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com