Exact(1)
While there are similarities, abnormalities unique to the Tc1 include increased levels of the S100B calcium-binding protein, mTOR proteins RAPTOR and P70S6, the AMP-kinase catalytic subunit AMPKA, the IEG proteins FBJ murine osteosarcoma viral oncogene homolog (CFOS) and activity-regulated cytoskeleton-associated protein (ARC), and the neuregulin 1 receptor ERBB4.
Similar(59)
21 The similarities in immunological abnormalities and treatment to another debilitating granulomatous disease, Crohn's disease, are striking.
Further investigation of differences (or similarities) in myelin abnormalities between FCD subtypes, with pathology-imaging coregistration, are warranted to improve pre-operative recognition and discrimination of these lesions.
This is due to the similarity of some abnormalities to vessels, and the low contrast between vessels and background of color retinal images which results in a similarity of color of vessels to color of background.
These alterations show remarkable similarities to the cutaneous abnormalities of patients with chloracne/ metabolizing acquired dioxin-induced skin hamartomas" (MADISH), a severe pathology that develops upon dioxin poisoning.
In the presence of benign cellular changes sharing some morphologic similarities with significant cervical abnormalities, the slide is triaged into the high-score group.
Although the observed NK dysfunction in a subgroup of patients with sJRA might not be of primary etiological significance for JRA itself, the similarities to the immunologic abnormalities seen in MAS and HLH suggest that depressed NK cell activity is likely to be relevant to the pathogenesis of MAS in sJRA.
The histopathological features of K5cre-CMVcaNrf2 mice showed remarkable similarities to the cutaneous abnormalities seen in patients with chloracne/MADISH (Saurat & Sorg, 2010), including hair follicle proliferation, hyperplasia, and hyperkeratosis as well as formation of keratinized cysts with small or no SGs (Fig 7A) (Panteleyev & Bickers, 2006).
The similarity of the intestinal abnormalities in both lop and hi559 larvae suggest that the mutant phenotype is not primarily an early developmental defect, but reflects a requirement for de novo PI in intestinal function at later larval stages.
With regards to neurons, they have been described to share many biochemical similarities [ 18– 20] and mirror abnormalities in psychiatric and neuronal disorders [ 21, 22].
The similarities and differences in reproductive abnormalities observed in humans and wildlife have stimulated fruitful interactions between toxicologists, epidemiologists, clinicians, ecotoxicologists and zoologists [ 4, 9].
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