The 5' part of both genes is highly conserved, with a mean identity rate among all 15 species of 74% and 62% for XPP and PAXP respectively (analysed on 97 and 109 bp, respectively); most mutations being silent, this yields identity rates at the amino acid level of 80%and78%78 % respectively.
Remarkably, severe nitrogen limitation during growth in a fully a controlled chemostat, induced polyketide biosynthesis genes that were otherwise silent and yielded two novel antiproliferative spiroanthrones, sanghaspirodins A and B (Scherlach et al. 2011).
Indeed, measuring S100B in the urine of asphyxiated newborns at a stage when standard diagnostic procedures are still silent or unreliable yields positive and negative predictive values relating to the early detection of infants at risk of ominous outcome.
Yielding the silent pristine wilderness of the North to the implantation of oil rigs because no one views them is an uncaring selfishness.
Using think-aloud protocol to probe into these silent instances might possibly yield more insights into the nature of acquiring and processing listening.
Of the latter SNPs, seven yielded a silent mutation and 6 SNPs introduced an amino acid change (Additional file 3: Table S2).
Yamanaka, K. et al. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.
