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However, in the particular case of pheomelanin, the broad vibrational peak of interest in this study is located in the 2000 2100 cm−1 range5,6, well within the so-called "silent region" of the Raman spectrum of biological samples13.
This condensed and transcriptionally silent region is essential for gene regulation, genome stability and chromosome segregation.
Each interburst interval occurs when the trajectory projected to ((na_{i}, ca_{i})) space lies in the silent region.
The wavelengths of the pump and the Stokes lasers (Pump = 870 nm and Stokes = 1064 nm) were tuned to match a Raman shift (~2100 cm−1), falling in the so-called "silent region" of the vibrational spectra of cells and tissues.
The wavelengths of the pump and the Stokes lasers (Pump = 870 nm and Stokes = 1064 nm) were tuned to match a Raman shift (~2100 cm−1) which falls in the so-called "silent region" of the vibrational spectra of cells and tissues.
Although the sequences for the two mating types must be different, the silent region and the expressed region to be replaced are located within homologous cassettes, which allow gene conversion to proceed.
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In contrast, the cells bearing single integration events decreased in frequency over time on therapy, and the surviving cells were enriched for HIV-1 integration in silent regions of the genome.
To examine whether Spt16 affects the binding of Sir2 4p to different silent regions, we performed chromatin immunoprecipitation (ChIP) assay using antibodies against Sir2 4p (Fig. 2A D).
Pseudogenes are typically more enriched relative to active genes in the heterochromatic and generally transcriptionally silent regions near centromeres [38].
Boxes 2 and 3 exemplify hypothetical scenarios for transcriptionally silent regions within the Barr body.
However, CBP binds to many silent regions without histone acetylation [ 21, 22].
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