In contrast, phosphorylation of isocitrate dehydrogenase revealed silent effects and no structural change in response to phosphorylation of the active site at Ser113.
Senator Mitch McConnell, the Republican leader who negotiated the two-month compromise with the Senate majority leader, Harry Reid, has been largely silent, in effect standing by his deal and letting House Republicans stew in the controversy.
Thus, it seems that prenatal exposure to maneb, rather than paraquat, may sensitise/predispose mice to development of PD (or lead to a state of increased vulnerability), whereas paraquat exposure later in life may unmask the silent toxic effect of the earlier maneb exposure and then lead to clinical symptoms of the disease.
They may not be subjectively aware of the toxic exposure, which may lead them into a false sense of security, especially as silent genotoxic effects may only become clinically manifest years after exposure [ 40- 43].
Silent phosphorylation effects can be observed where there is no conformational change induced in the RNA-binding protein, and the negative charge and steric bulk of the phosphate directly alters its association with an effector protein or RNA.
Most of our empirical knowledge of CGV arises from studies that inhibited the heat shock chaperone protein HSP90 to reveal previously-silent mutational effects across many taxa, which probably represents a general mechanism that buffers genome-wide functional variation (Queitsch et al., 2002; Yeyati et al., 2007; Jarosz and Lindquist, 2010; Chen and Wagner, 2012; Rohner et al., 2013).
But German regulators had long allowed their banks to include in the "core" securities with a much shorter maturity, dubbed "silent partnerships"—in effect, subordinated preference shares.
Mr. Simmons' letter in the annual report did mention there was a change in accounting rules but was silent on its effect.
The economy is run according to "distributivism", a form of property-owning capitalism inspired by GK Chesterton and Hilaire Belloc, while the Saudis and Qataris vie for influence over the Arabs' new home from home (Houellebecq is silent on what effect this will have on property prices in Knightsbridge).
These share buybacks are, in effect, silent dividends.
