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Have years of appeasement -- intellectual and political -- led to a silent conversion?
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A somewhat different use of gene conversion between silent and expressed cassettes takes place in numerous disease microbes (pathogens), both bacteria and eukaryotes.
By spontaneously switching expression at a single expression locus by gene conversion from silent genes RF spirochetes evade antibody-mediated clearance [2].
Combined with the increased abundance of functionally mature spines, the selective impact on the frequency of miniEPSCs may be attributable to the neuritin-mediated conversion of silent synapses into functional synapses, involving incorporation of AMPA receptors into pure-N-methyl D-aspartate (NMDA) receptor synapses.
In the optic tectal neurons of X. laevis, expression of full-length neuritin promoted axonal outgrowth or dendritic branching, as well as conversion of silent synapses into functional synapses, whereas the truncated form of neuritin lacking the GPI sequence did not.
Unlike these approaches, our strategy focused on activation of the endogenous but often silent Sbm operon for extended conversion of succinate into 1-propanol.
In about 60% of male X-ALD patients, either in childhood (35 40%) or in adulthood (20%), an initial, clinically silent, myelin destabilization results in conversion to a devastating, rapidly progressive form of cerebral inflammatory demyelination.
Rare conversions between the silent and active states confer a quasi-stable pattern of epigenetically controlled gene expression in the vicinity of the telomeres [ 53].
"The pension conversion seems to be this silent thing happening out there in America," he said.
Loss of AMPAR from spines may result in conversion of functional synapses into silent, non-functional synapses (Lo and Erzurumlu, 2007).
The vast majority of FBO/Robertson-Cole pictures, produced during either the silent era or the transitional period of the conversion to sound cinema, are considered to be lost films, with no copies now known to exist.
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