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Thereby, CRP binding improves opsonization and phagocytosis of apoptotic cells by macrophages, and promotes their silent clearance [71].
Defects in silent clearance of apoptotic remnants before necrosis might prevent processes of the physiological maintenance of tissue integrity to operate [ 53].
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Macrophages and MGCs are also crucial for the clinically silent physiological clearance of autologous debris and for tissue remodeling after injury, such as the elimination of hematomas or the remodeling of bone, respectively.
But the Chinese have been silent so far; without clearance from the censor, the film could not find a spot on this year's schedule in China, where the number of foreign releases is tightly restricted.
However, after treatment with CPHPC, immunoglobulin G anti-SAP antibodies can be safely administered and can then reach and bind to the amyloid deposits where they trigger very effective, clinically silent, complement dependent, macrophage-mediated clearance of the amyloid.
The most extensively studied example of a silent uptake into phagocytes is the clearance of apoptotic cells which is a well organized three step process [16].
By spontaneously switching expression at a single expression locus by gene conversion from silent genes RF spirochetes evade antibody-mediated clearance [2].
The physiological clearance of tissue granulocytes is normally silent, but can under certain situations shift to become a pro-inflammatory event.
However, it has recently been shown that antibodies to PEG can cause silent inactivation by depleting the serum of ASNase through clearance of the PEG conjugates, rendering the treatment ineffective.
Indeed, that SLE may reflect an autoimmune response to debris from 'apoptotic' cells, despite clearance of such material being thought generally immunologically silent [ 7], has been a conundrum.
After Myler had failed to convert Dowson's try, they ran the ball from their own line in the final minute and when Foden was forced to make a hurried clearance, Andreu left the large contingent of travelling supporters silent for the first time on the night.
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CEO of Professional Science Editing for Scientists @ prosciediting.com