The prognosis of this malignancy is poor due to its silent clinical characteristics, difficulties in early diagnosis, and limited therapeutic measures.
The absence of statistically significant alterations in the hematologic parameters between infected and non-infected rats is consistent with the low pathogenicity and/or silent infection characteristics of these microorganisms.
On the ground floor of Din Tai Fung is a glass-walled kitchen where cooks make dumplings in a display of silent concentration characteristic of a high-end electronics factory.
All Haarlem strains carried one characteristic silent mutation in mutT3 and one characteristic mutation in ogt (Ser 15 replaced by Thr).
They developed a model in which the choice to remain silent is driven by individual characteristics, organizational characteristics, relationship with the supervisor, anticipated negative outcomes, and the belief that speaking up will not make a difference [ 13].
The optimal IEL lymphogram cut off values for active CD diagnosis were: ≥10, ≥15 and ≤9 %, and with better performance characteristics for silent CD: ≥ 11, ≥10 and ≤5 %.
In particular, the hypomethylation of H3-K4 and H3-K79 is the characteristics of silent chromatin [11], [20].
Several sequences located within TgTAS-like regions were previously reported to hold characteristics of silent chromatin.
On the basis of the work noted above, and much evidence that CpG hypermethylation is characteristic of silent retroelements, we expected that pseudoagouti mice would display the opposite pattern: dense CpG methylation.
In fact, two clinically silent lesions in locations characteristic of MS (i.e. periventricular, juxtacortical, infratentorial or spinal cord) performed very well in this setting [ 13].
