Sentence examples for silence information from inspiring English sources

Resveratrol, a Silence Information Regulator 1 (SIRT1) activator, induces apoptosis MH7A human rheumatoid arthritis synovial cells in a SIRT1-dependent manner [ 23].

The three Sir (silence information regulator) proteins are part of the Sir silencing complex, which is also needed for transcriptional repression at the two silent mating type loci, HML and HMR.

To date, it is still unclear if Silence Information Regulator 1 (SIregulateslates cell cycle regulators in the proliferation of PASMCs and contributes to prevention of PAH by resveratrol.

We used 5 independently transformed EVC lines containing the pRESC2NC vector construct that lacks the silencing information and carries a hygromycin-resistance gene, as described in [17], [33].

Four rice genes, Pyruvate Dehydrogenase Kinase 1 and 2 (OsPDK1 and OsPDK2), Silencing Information Regulator 2 (OsSRT1), and Metallothionein2b (OsMT2b), were selected for our studies.

Sirtuins are orthologs of yeast Sir2 (silencing information regulator) [2], [3], which mediates chromatin silencing [4], [5] and slows the aging rate by suppressing the production of extrachromosomal rDNA circles [6].

In regard to the latter, an orthologue of the S. cerevisiae NAD+ dependent histone deacetylase (HDAC) sir2 (Silencing Information Regulator 2, also known as sirtuin), involved in alteration in chromatin structure was identified in P. falciparum and termed pfsir2 [24].

The founding member of sirtuin is the yeast-silencing information regulator 2 (SIR2) protein, one of four proteins (SIR1 4) required for silencing the mating-type information loci in yeast.

However, it appears that as the telomeres shorten, silencing information is removed, leading to the expression of the YRF1 genes [ 31].

By use of in vivo chromatin immunoprecipitation (ChIP), lrs mutants have been shown to have reduced binding of the yeast silencing information regulatory (SIR) proteins at loci normally targeted for silencing.

These mutations could potentially remove silencing information for these genes; the genotype at the eQTL hotspot is indicative of the expression level in both cases (p-value = 1e-4 and 1e-6 respectively).