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The genes within the causal network represent nodes and the edge that defines the biological relationship between two nodes is represented as an arrow signifying regulation.
Similar(59)
Positive or negative regulation of a TF on a pathway signifies that the regulations on different pathway genes are constant and don't change with experiments.
With luck, greater flexibility will signify that regulators are stepping back and that 3G will mark the high-water mark for aggressive regulation.
Interestingly, one type 2B mutant, R167Q, was unstable yet retained normal HIF-2α regulation in our assays, signifying that deficiencies in stability and VHL function are not synonymous.
"Statutory regulation would signify the importance that should be attached to ethical conduct in public office," they said.
Signal-induced phosphorylation of MAPKs increases their activity [1], while dephosphorylation by protein phosphatases reverts the MAPK modules to an inactive state, signifying MAPK phosphatases as part of the mechanisms to ensure dynamics and tight regulation of signaling pathways.
But signifying what?
The down-regulation of four of these transcripts MYL1, ACTA1, TCAP and DESMIN in buccal cancer were further supported by quantitative PCR signifying its possible implication in the cancer progression.
Sound and fury signifying nothing.
Signifying nothing.
And signifying.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com