Exact(19)
The thrust of Kumārila's argument can be brought out by briefly contrasting this epistemological position with what Mīmāṃsakas not unreasonably took to be the characteristically Buddhist position in this regard (with its being particularly the thought of the Buddhists Dignāga and Dharmakīrti that Mīmāṃsakas most significantly targeted with their epistemological arguments).
Notably, the biological processes and the signaling pathways most significantly targeted by the effectors on our list were actin cytoskeleton organization, cell growth, and apoptosis (Table 1).
However when adjusting for multiple testing using the Bonferroni method only two pathways significantly targeted by genomic alterations are also highly associated with survival;""Hypoxic and oxygen homeostasis regulation of HIF-1-alpha" [38], [39], [40], and Glycosaminoglycan degradation [refs].
Furthermore, molecules that significantly targeted the same pathways tended to treat the same diseases.
Several biological pathways that are well characterised in cancer are significantly targeted by the downregulated miRNAs.
The third signalling pathway, significantly targeted by down-modulated miRNAs, is the VEGF-regulated angiogenesis.
Similar(41)
In vivo, a single administration of MSC-3TSR/S-TRAIL significantly targets both tumor cells and vascular component of GBMs, inhibits tumor progression, and extends survival of mice bearing highly vascularized GBM.
Zara and Topshop are two retailers that have opened much-hyped flagships here in the last two years, and there are countless fast fashion online retailers significantly targeting Australia.
Additional data in this study also show that Tax does not significantly target XRCC4 or H2AX.
A link was placed between a molecule and a pathway if the molecule significantly targets the pathway.
Suppose the adjacency matrix was A. When A ij = 1, then that small molecule i significantly targets pathway j.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com