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To analyze the spatial relationship of those apparently correlated astrocytes, we segregated pairs of active astrocytes that are significantly synchronized by means of the Fisher's exact test (see Methods).
Out of 2662 (L1: 2481, L2/3: 181) pairs of active astrocytes, 382 (L2/3356, L2/3: 26) pairs were found to be significantly synchronized (p<0.01), and 2038 (L1: 1886, L2/3: 152) pairs had p values larger than 0.05 in the Fisher's exact test which we defined as the non-synchronous pairs.
Voxels with a coherence value greater than 0.35 were considered to be significantly synchronized to stimulation.
While these data are not sufficient to decisively conclude the underlying mechanism, they suggest that dynamics across the recorded regions are significantly synchronized, with small but detectable phase delays across cortical sites.
Cross-frequency coupling results, however, demonstrate that there was indeed task-related gamma activity over posterior electrodes, but the transient nature of these gamma "bursts" were such that they were significantly synchronized with alpha phase but were sufficiently jittered that they were difficult to observe in response-locked trial averaging.
Both locally in the thalamus and at downstream, synaptically connected brain regions, the frequency of stimulation was a critical parameter in determining the extent of ipsilateral and contralateral BOLD activation – defined here as positive BOLD signals significantly synchronized to the block stimulation paradigm (see 'Materials and methods').
Similar(52)
Using extensive TB surveillance data on the San Francisco homeless, we found that the evolution of TB cases and their HIV+/PPD− contacts is significantly interdependent, synchronized at about every 2.5 years and separated by the mean lag time of 5.4 months.
We observed that the levels of both AURKA and AURKB were significantly higher in synchronized melanoma cell lines than in synchronized normal melanocytes (Supporting Information Fig S1A).
Altogether, these data indicate that lack of GSTP1/P2 significantly impaired the partially synchronized first wave of hepatocyte proliferation without abolishing totally the process of liver regeneration.
Patients randomized to personalized audio-playlists with tempo-pace synchronized music embarked on significantly greater amounts of weekly physical activity and experienced lower declines in weekly physical activity than did their non-music usual-care counterparts.
This percentage of post stimulus evoked synchronized spontaneous responses was significantly higher than the basal rate of such occurrences (6%) in the absence of any extracellular stimulus (Chi-square test: p<0.0001).
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