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Notably, there was a significantly spared rim of white matter in the SNS group, even at the lesion epicenter, whereas the control group exhibited severely demyelinated white matter throughout the lesioned area (2 mm rostral and caudal to the lesion epicenter) (Fig. 2C and D).
Blocking FoxO prevented C26-induced muscle fiber atrophy of both locomotor muscles and the diaphragm and significantly spared force deficits.
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High style is back in men's fashion, and Baldwin's particular brand of modernism -- a snappy, sartorial splendor he perfected along with his significantly spare, but always classic, interior design work -- was evident in many of the recent collections.
Intensity-modulated radiotherapy can significantly spare the lungs from irradiation.
Therefore, prompt inhibition of calpains, if undertaken early enough after injury, could significantly spare lots of neurons.
In fact, a delay as short as 2.6 hr was sufficient to significantly spare the number of LT-HSC divisions.
These tissues are either within the prostate or immediately adjacent to it and are unlikely to be significantly further spared without undertreating the prostate itself.
We found that the probability of failure at excitatory connections between pairs of L2/3 pyramidal neurons was significantly lower in spared cortex (0.00 [0.00–0.08], n = 10; Materials and Methods) than that in control cortex (0.34 [0.06–0.59], n = 13; P = 0.020, Mann Whitney rank sum test; Fig. 5 A, B).
Salehi et al. reported significantly better recovery of rat hindlimb motor function, which was accompanied by significantly greater percentage of spared tissue, axon regeneration, and remyelination in the cotransplantation group of OECs and embryonic stem cell-derived motor neurons, when compared with the other single-celltype groups [ 57].
This cotransplantation strategy rescued a significantly greater percentage of spared spinal cord tissue from contused lesion, and successfully enhanced remyelination after injury.
Children 10 years of age who were born with larger head size relative to body weight (i.e., "brain spared") scored significantly lower in neuro-developmental tests, IQ, and school performances (Leitner et al. 2007).
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